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Selective elimination of cancer cells by the adenovirus E4orf4 protein in a Drosophila cancer model: a new paradigm for cancer therapy

The adenovirus (Ad) E4orf4 protein contributes to efficient progression of virus infection. When expressed alone E4orf4 induces p53- and caspase-independent cell-death, which is more effective in cancer cells than in normal cells in tissue culture. Cancer selectivity of E4orf4-induced cell-death may...

詳細記述

保存先:
書誌詳細
出版年:Cell Death Dis
主要な著者: Rosen, Helit, Sharf, Rakefet, Pechkovsky, Antonina, Salzberg, Adi, Kleinberger, Tamar
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6560070/
https://ncbi.nlm.nih.gov/pubmed/31186403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1680-4
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