Selection of Apoptosis-Deficient Adenovirus E4orf4 Mutants in Saccharomyces cerevisiae

Adenovirus E4orf4 protein has been shown to induce p53-independent, protein phosphatase 2A (PP2A)-dependent apoptosis in transformed cells. Furthermore, E4orf4 also induces toxicity in Saccharomyces cerevisiae in a PP2A-dependent manner (D. Kornitzer and T. Kleinberger, submitted for publication). I...

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Detalhes bibliográficos
Main Authors: Afifi, Rana, Sharf, Rakefet, Shtrichman, Ronit, Kleinberger, Tamar
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Replication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC114194/
https://ncbi.nlm.nih.gov/pubmed/11287598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.9.4444-4447.2001
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