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The Adenovirus E4orf4 Protein Provides a Novel Mechanism for Inhibition of the DNA Damage Response.

The DNA damage response (DDR) is a conglomerate of pathways designed to detect DNA damage and signal its presence to cell cycle checkpoints and to the repair machinery, allowing the cell to pause and mend the damage, or if the damage is too severe, to trigger apoptosis or senescence. Various DDR bra...

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Bibliografiske detaljer
Principais autores: Anna Brestovitsky, Keren Nebenzahl-Sharon, Peter Kechker, Rakefet Sharf, Tamar Kleinberger
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science (PLoS) 2016-02-01
Serier:PLoS Pathogens
Online adgang:http://europepmc.org/articles/PMC4750969?pdf=render
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