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Selection of Apoptosis-Deficient Adenovirus E4orf4 Mutants in Saccharomyces cerevisiae

Adenovirus E4orf4 protein has been shown to induce p53-independent, protein phosphatase 2A (PP2A)-dependent apoptosis in transformed cells. Furthermore, E4orf4 also induces toxicity in Saccharomyces cerevisiae in a PP2A-dependent manner (D. Kornitzer and T. Kleinberger, submitted for publication). I...

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Udgivet i:J Virol
Principais autores: Afifi, Rana, Sharf, Rakefet, Shtrichman, Ronit, Kleinberger, Tamar
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2001
Fag:
Replication
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC114194/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11287598/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.75.9.4444-4447.2001
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