Structure- and Modeling-based Identification of the Adenovirus E4orf4 Binding Site in the Protein Phosphatase 2A B55α Subunit

The adenovirus E4orf4 protein regulates the progression of viral infection and when expressed outside the context of the virus it induces nonclassical, cancer cell-specific apoptosis. All E4orf4 functions known to date require an interaction between E4orf4 and protein phosphatase 2A (PP2A), which is...

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Bibliographische Detailangaben
Hauptverfasser: Horowitz, Ben, Sharf, Rakefet, Avital-Shacham, Meirav, Pechkovsky, Antonina, Kleinberger, Tamar
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2013
Schlagworte:
Computational Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3650409/
https://ncbi.nlm.nih.gov/pubmed/23530045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.343756
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