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NTPDASE4 Gene Products Cooperate with the Adenovirus E4orf4 Protein through PP2A-Dependent and -Independent Mechanisms and Contribute to Induction of Cell Death

The adenovirus E4orf4 protein induces nonclassical apoptosis in mammalian cells through at least two complementing pathways regulated by the interactions of E4orf4 with protein phosphatase 2A (PP2A) and Src kinases. In Saccharomyces cerevisiae cells, which do not express Src, E4orf4 induces PP2A-dep...

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Библиографические подробности
Главные авторы: Avital-Shacham, Meirav, Sharf, Rakefet, Kleinberger, Tamar
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2014
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4093884/
https://ncbi.nlm.nih.gov/pubmed/24672025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00381-14
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