Adenovirus E4orf4 protein induces PP2A-dependent growth arrest in Saccharomyces cerevisiae and interacts with the anaphase-promoting complex/cyclosome

Adenovirus early region 4 open reading frame 4 (E4orf4) protein has been reported to induce p53-independent, protein phosphatase 2A (PP2A)–dependent apoptosis in transformed mammalian cells. In this report, we show that E4orf4 induces an irreversible growth arrest in Saccharomyces cerevisiae at the...

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Autores principales: Kornitzer, Daniel, Sharf, Rakefet, Kleinberger, Tamar
Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 2001
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Research Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2150760/
https://ncbi.nlm.nih.gov/pubmed/11470822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200104104
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