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The adenovirus E4orf4 protein targets PP2A to the ACF chromatin-remodeling factor and induces cell death through regulation of SNF2h-containing complexes

The adenovirus E4 open-reading-frame 4 (E4orf4) protein regulates the progression of viral infection and when expressed individually it induces non-classical apoptosis in transformed cells. Here we show that E4orf4 associates with the ATP-dependent chromatin-remodeling factor ACF that consists of a...

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Main Authors: Brestovitsky, Anna, Sharf, Rakefet, Mittelman, Karin, Kleinberger, Tamar
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3159439/
https://ncbi.nlm.nih.gov/pubmed/21546548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr231
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