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The Adenovirus E4orf4 Protein Provides a Novel Mechanism for Inhibition of the DNA Damage Response

The DNA damage response (DDR) is a conglomerate of pathways designed to detect DNA damage and signal its presence to cell cycle checkpoints and to the repair machinery, allowing the cell to pause and mend the damage, or if the damage is too severe, to trigger apoptosis or senescence. Various DDR bra...

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Detalles Bibliográficos
Publicado en:PLoS Pathog
Main Authors: Brestovitsky, Anna, Nebenzahl-Sharon, Keren, Kechker, Peter, Sharf, Rakefet, Kleinberger, Tamar
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4750969/
https://ncbi.nlm.nih.gov/pubmed/26867009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005420
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