The Adenovirus E4orf4 Protein Provides a Novel Mechanism for Inhibition of the DNA Damage Response

The DNA damage response (DDR) is a conglomerate of pathways designed to detect DNA damage and signal its presence to cell cycle checkpoints and to the repair machinery, allowing the cell to pause and mend the damage, or if the damage is too severe, to trigger apoptosis or senescence. Various DDR bra...

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Bibliographische Detailangaben
Veröffentlicht in:PLoS Pathog
Hauptverfasser: Brestovitsky, Anna, Nebenzahl-Sharon, Keren, Kechker, Peter, Sharf, Rakefet, Kleinberger, Tamar
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2016
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4750969/
https://ncbi.nlm.nih.gov/pubmed/26867009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005420
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