Chargement en cours...

Generating conformation-specific synthetic antibodies to trap proteins in selected functional states

A set of phage display sorting strategies and validation methodologies are presented that are capable of producing high performance synthetic antibodies (sABs) with customized properties. Exquisite control of antigen and conditions during the phage display selection process can yield sABs that: 1) r...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Paduch, Marcin, Koide, Akiko, Uysal, Serdar, Rizk, Shahir S., Koide, Shohei, Kossiakoff, Anthony A.
Format: Artigo
Langue:Inglês
Publié: 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3650108/
https://ncbi.nlm.nih.gov/pubmed/23280336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2012.12.010
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!