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An engineered substance P variant for receptor-mediated delivery of synthetic antibodies into tumor cells
We have developed and tested a robust delivery method for the transport of proteins to the cytoplasm of mammalian cells without compromising the integrity of the cell membrane. This receptor-mediated delivery (RMD) technology utilizes a variant of substance P (SP), a neuropeptide that is rapidly int...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2708752/ https://ncbi.nlm.nih.gov/pubmed/19549879 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0904907106 |
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