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An engineered substance P variant for receptor-mediated delivery of synthetic antibodies into tumor cells

We have developed and tested a robust delivery method for the transport of proteins to the cytoplasm of mammalian cells without compromising the integrity of the cell membrane. This receptor-mediated delivery (RMD) technology utilizes a variant of substance P (SP), a neuropeptide that is rapidly int...

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Hlavní autoři: Rizk, Shahir S., Luchniak, Anna, Uysal, Serdar, Brawley, Crista M., Rock, Ronald S., Kossiakoff, Anthony A.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2708752/
https://ncbi.nlm.nih.gov/pubmed/19549879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0904907106
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