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Short artificial hairpins sequester splicing signals and inhibit yeast pre-mRNA splicing.

To examine the stability of yeast (Saccharomyces cerevisiae) pre-mRNA structures, we inserted a series of small sequence elements that generated potential RNA hairpins at the 5' splice site and branch point regions. We analyzed spliceosome assembly and splicing in vitro as well as splicing and nucle...

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Vydáno v:Mol Cell Biol
Hlavní autoři: Goguel, V, Wang, Y, Rosbash, M
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 1993
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC364746/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8413277/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.13.11.6841-6848.1993
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