Short artificial hairpins sequester splicing signals and inhibit yeast pre-mRNA splicing.

To examine the stability of yeast (Saccharomyces cerevisiae) pre-mRNA structures, we inserted a series of small sequence elements that generated potential RNA hairpins at the 5' splice site and branch point regions. We analyzed spliceosome assembly and splicing in vitro as well as splicing and nucle...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Goguel, V, Wang, Y, Rosbash, M
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 1993
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC364746/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8413277/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.13.11.6841-6848.1993
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