Short artificial hairpins sequester splicing signals and inhibit yeast pre-mRNA splicing.
To examine the stability of yeast (Saccharomyces cerevisiae) pre-mRNA structures, we inserted a series of small sequence elements that generated potential RNA hairpins at the 5' splice site and branch point regions. We analyzed spliceosome assembly and splicing in vitro as well as splicing and nucle...
שמור ב:
| הוצא לאור ב: | Mol Cell Biol |
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| Principais autores: | , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Taylor & Francis
1993
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC364746/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8413277/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.13.11.6841-6848.1993 |
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