The relationship of polymorphisms in ABCC2 and SLCO1B3 with docetaxel pharmacokinetics and neutropenia: CALGB 60805 (Alliance)

Docetaxel-related neutropenia was associated with polymorphisms in the drug transporters ABCC2 and SLCO1B3 in Japanese cancer patients. We hypothesized that this association is because of reduced docetaxel clearance, associated with polymorphisms in those genes. We studied 64 US cancer patients who...

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Xehetasun bibliografikoak
Egile Nagusiak: Lewis, Lionel D., Miller, Antonius A., Owzar, Kouros, Bies, Robert R., Markova, Svetlana, Jiang, Chen, Kroetz, Deanna L., Egorin, Merrill J., McLeod, Howard L., Ratain, Mark J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2013
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3647228/
https://ncbi.nlm.nih.gov/pubmed/23188068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FPC.0b013e32835b16d8
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