Effect of Age on the Pharmacokinetics of Busulfan in Patients Undergoing Hematopoietic Cell Transplantation; an Alliance study (CALGB 10503, 19808, and 100103)

PURPOSE: Older patients with acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS) have often been excluded from myeloablative conditioning regimens containing busulfan because of non-disease related morbidity and mortality. We hypothesized that busulfan clearance (BuCL) in older patients...

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Detalhes bibliográficos
Main Authors: Beumer, Jan H., Owzar, Kouros, Lewis, Lionel D., Jiang, Chen, Holleran, Julianne L., Christner, Susan M., Blum, William, Devine, Steven, Kolitz, Jonathan E., Linker, Charles, Vij, Ravi, Alyea, Edwin P, Larson, Richard A., Ratain, Mark J., Egorin, Merrill J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4210372/
https://ncbi.nlm.nih.gov/pubmed/25163570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-014-2571-0
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