Effect of Age on the Pharmacokinetics of Busulfan in Patients Undergoing Hematopoietic Cell Transplantation; an Alliance study (CALGB 10503, 19808, and 100103)

PURPOSE: Older patients with acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS) have often been excluded from myeloablative conditioning regimens containing busulfan because of non-disease related morbidity and mortality. We hypothesized that busulfan clearance (BuCL) in older patients...

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書誌詳細
主要な著者: Beumer, Jan H., Owzar, Kouros, Lewis, Lionel D., Jiang, Chen, Holleran, Julianne L., Christner, Susan M., Blum, William, Devine, Steven, Kolitz, Jonathan E., Linker, Charles, Vij, Ravi, Alyea, Edwin P, Larson, Richard A., Ratain, Mark J., Egorin, Merrill J.
フォーマット: Artigo
言語:Inglês
出版事項: 2014
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4210372/
https://ncbi.nlm.nih.gov/pubmed/25163570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-014-2571-0
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