Rapamycin inhibits FBXW7 loss-induced epithelial-mesenchymal transition and cancer stem cell-like characteristics in colorectal cancer cells

Increased cell migration and invasion lead to cancer metastasis and are crucial to cancer prognosis. In this study, we explore whether FBXW7 plays any role in metastatic process. We show that depletion of FBXW7 induces epithelial-mesenchymal transition (EMT) in human colon cancer cells along with th...

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Main Authors: Wang, Yuli, Liu, Yueyong, Lu, Jing, Zhang, Pengju, Wang, Yunshan, Xu, Yangyang, Wang, Zeran, Mao, Jian-Hua, Wei, Guangwei
Formato: Artigo
Idioma:Inglês
Publicado: 2013
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3646979/
https://ncbi.nlm.nih.gov/pubmed/23558291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2013.03.077
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