FBXW7 suppresses epithelial-mesenchymal transition, stemness and metastatic potential of cholangiocarcinoma cells

Epithelial-mesenchymal transition (EMT) plays a fundamental role in cancer metastasis. The ubiquitin ligase FBXW7, a general tumor suppressor in human cancer, has been implicated in diverse cellular processes, however, its role in cholangiocarcinoma (CCA) metastasis has not been identified. Here, we...

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Detalles Bibliográficos
Publicado en:Oncotarget
Main Authors: Yang, Hui, Lu, Xiaofei, Liu, Ziming, Chen, Lili, Xu, Yunfei, Wang, Yuli, Wei, Guangwei, Chen, Yuxin
Formato: Artigo
Idioma:Inglês
Publicado: Impact Journals LLC 2015
Assuntos:
Research Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4467439/
https://ncbi.nlm.nih.gov/pubmed/25749036
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