Upregulation of FBXW7 Suppresses Renal Cancer Metastasis and Epithelial Mesenchymal Transition

BACKGROUND AND OBJECTIVE: FBXW7, known as a general tumor suppressor, is commonly lowly expressed in metastatic malignancies. We aim to investigate the potential influence of FBXW7 overexpression on renal cell carcinoma (RCC) metastasis. METHODS: We employed quantitative real-time PCR (qRT-PCR) and...

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Bibliographic Details
Published in:Dis Markers
Main Authors: Cai, Yangke, Zhang, Meng, Qiu, Xiaofu, Wang, Bingwei, Fu, Yu, Zeng, Jun, Bai, Jian, Yang, Guosheng
Format: Artigo
Language:Inglês
Published: Hindawi 2017
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5643092/
https://ncbi.nlm.nih.gov/pubmed/29097832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/8276939
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