CUL4A induces epithelial-mesenchymal transition and promotes cancer metastasis by regulating ZEB1 expression

The ubiquitin ligase CUL4A has been implicated in tumorigenesis but its contributions to progression and metastasis have not been evaluated. Here we show that CUL4A is elevated in breast cancer as well as ovarian, gastric and colorectal tumors where its expression level correlates positively with di...

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Bibliografiset tiedot
Päätekijät: Wang, Yunshan, Wen, Mingxin, Kwon, Yongwon, Xu, Yangyang, Liu, Yueyong, Zhang, Pengju, He, Xiuquan, Wang, Qin, Huang, Yurong, Jen, Kuang-Yu, LaBarge, Mark A, You, Liang, Kogan, Scott C, Gray, Joe W, Mao, Jian-Hua, Wei, Guangwei
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2013
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3934357/
https://ncbi.nlm.nih.gov/pubmed/24305877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-13-2182
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