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Distinct interactions of EBP1 isoforms with FBXW7 elicits different functions in cancer

The ErbB3 receptor binding protein EBP1 encodes two alternatively spliced isoforms p48 and p42. While there is evidence of differential roles for these isoforms in tumorigenesis, little is known about their underlying mechanisms. Here we demonstrate that EBP1 isoforms interact with the SCF-type ubiq...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Wang, Yuli, Zhang, Pengju, Wang, Yunshan, Zhan, Panpan, Liu, Chunyan, Mao, Jian-Hua, Wei, Guangwei
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5392370/
https://ncbi.nlm.nih.gov/pubmed/28209614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-16-2246
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