FBXW7 negatively regulates ENO1 expression and function in colorectal cancer

FBXW7 (F-box and WD40 domain protein 7) is a tumor suppressor frequently inactivated in human cancers. The precise molecular mechanisms by which FBXW7 exerts antitumor activity remain under intensive investigation and are thought to relate in part to FBXW7-mediated destruction of key cancer-relevant...

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Bibliographic Details
Published in:Lab Invest
Main Authors: Zhan, Panpan, Wang, Yuli, Zhao, Shihu, Liu, Chunyan, Wang, Yunshan, Wen, Mingxin, Mao, Jian-Hua, Wei, Guangwei, Zhang, Pengju
Format: Artigo
Language:Inglês
Published: 2015
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4552619/
https://ncbi.nlm.nih.gov/pubmed/26097998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/labinvest.2015.71
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