Enhanced beta cell proliferation in mice overexpressing a constitutively active form of Akt and one allele of p21(Cip)

AIMS/HYPOTHESIS: The ability of pancreatic beta cells to proliferate is critical both for normal tissue maintenance and in conditions where there is an increased demand for insulin. Akt (also known as Protein kinase B) plays a major role in promoting proliferation in many cell types, including the i...

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Bibliografski detalji
Glavni autori: Blandino-Rosano, M., Alejandro, E. U., Sathyamurthy, A., Scheys, J. O., Gregg, B., Chen, A. Y., Rachdi, L., Weiss, A., Barker, D. J., Gould, A. P., Elghazi, L., Bernal-Mizrachi, E.
Format: Artigo
Jezik:Inglês
Izdano: 2012
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3646796/
https://ncbi.nlm.nih.gov/pubmed/22327314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-012-2465-9
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