MPN patients harbor recurrent truncating mutations in transcription factor NF-E2

The molecular etiology of myeloproliferative neoplasms (MPNs) remains incompletely understood, despite recent advances incurred through the discovery of several different mutations in MPN patients. We have recently described overexpression of the transcription factor NF-E2 in MPN patients and shown...

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Autores principales: Jutzi, Jonas S., Bogeska, Ruzhica, Nikoloski, Gorica, Schmid, Corina A., Seeger, Thalia S., Stegelmann, Frank, Schwemmers, Sven, Gründer, Albert, Peeken, Jan C., Gothwal, Monika, Wehrle, Julius, Aumann, Konrad, Hamdi, Kamar, Dierks, Christine, Wang, Wei, Döhner, Konstanze, Jansen, Joop H., Pahl, Heike L.
Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 2013
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3646501/
https://ncbi.nlm.nih.gov/pubmed/23589569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20120521
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