HIF proteins connect the RB-E2F factors to angiogenesis

Recently, we showed that E2F7 and E2F8 (E2F7/8) are critical regulators of angiogenesis through transcriptional control of VEGFA in cooperation with HIF.(1) Here we investigate the existence of other novel putative angiogenic E2F7/8-HIF targets, and discuss the role of the RB-E2F pathway in regulati...

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Bibliografiske detaljer
Main Authors: Bakker, Walbert. J., Weijts, Bart G.M.W., Westendorp, Bart, de Bruin, Alain
Format: Artigo
Sprog:Inglês
Udgivet: Landes Bioscience 2013
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3646055/
https://ncbi.nlm.nih.gov/pubmed/23412359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/trns.23680
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