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Loss of Pten promotes angiogenesis and enhanced vegfaa expression in zebrafish

Angiogenesis, the emergence of vessels from an existing vascular network, is pathologically associated with tumor progression and is of great interest for therapeutic intervention. PTEN is a frequently mutated tumor suppressor and has been linked to the progression of many types of tumors, including...

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Main Authors: Choorapoikayil, Suma, Weijts, Bart, Kers, Rianne, de Bruin, Alain, den Hertog, Jeroen
格式: Artigo
語言:Inglês
出版: The Company of Biologists Limited 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3759335/
https://ncbi.nlm.nih.gov/pubmed/23720233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.012377
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