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Differential Requirement for Pten Lipid and Protein Phosphatase Activity during Zebrafish Embryonic Development

The lipid- and protein phosphatase PTEN is one of the most frequently mutated tumor suppressor genes in human cancers and many mutations found in tumor samples directly affect PTEN phosphatase activity. In order to understand the functional consequences of these mutations in vivo, the aim of our stu...

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Publicat a:PLoS One
Autors principals: Stumpf, Miriam, den Hertog, Jeroen
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4743836/
https://ncbi.nlm.nih.gov/pubmed/26848951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0148508
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