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Differential Requirement for Pten Lipid and Protein Phosphatase Activity during Zebrafish Embryonic Development

The lipid- and protein phosphatase PTEN is one of the most frequently mutated tumor suppressor genes in human cancers and many mutations found in tumor samples directly affect PTEN phosphatase activity. In order to understand the functional consequences of these mutations in vivo, the aim of our stu...

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Bibliographic Details
Published in:PLoS One
Main Authors: Stumpf, Miriam, den Hertog, Jeroen
Format: Artigo
Language:Inglês
Published: Public Library of Science 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4743836/
https://ncbi.nlm.nih.gov/pubmed/26848951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0148508
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