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Atypical E2Fs inhibit tumor angiogenesis

Atypical E2F transcription factors (E2F7 and E2F8) function as key regulators of cell cycle progression and their inactivation leads to spontaneous cancer formation in mice. However, the mechanism of the tumor suppressor functions of E2F7/8 remain obscure. In this study we discovered that atypical E...

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Detalhes bibliográficos
Publicado no:Oncogene
Main Authors: Weijts, B G M W, Westendorp, B, Hien, B T, Martínez-López, L M, Zijp, M, Thurlings, I, Thomas, R E, Schulte-Merker, S, Bakker, W J, de Bruin, A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5770600/
https://ncbi.nlm.nih.gov/pubmed/28925392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2017.336
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