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E2F7 and E2F8 promote angiogenesis through transcriptional activation of VEGFA in cooperation with HIF1

The E2F family of transcription factors plays an important role in controlling cell-cycle progression. While this is their best-known function, we report here novel functions for the newest members of the E2F family, E2F7 and E2F8 (E2F7/8). We show that simultaneous deletion of E2F7/8 in zebrafish a...

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Detaylı Bibliyografya
Asıl Yazarlar: Weijts, Bart G M W, Bakker, Walbert J, Cornelissen, Peter W A, Liang, Kuo-Hsuan, Schaftenaar, Frank H, Westendorp, Bart, de Wolf, Charlotte A C M T, Paciejewska, Maya, Scheele, Colinda L G J, Kent, Lindsey, Leone, Gustavo, Schulte-Merker, Stefan, de Bruin, Alain
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2012
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3463843/
https://ncbi.nlm.nih.gov/pubmed/22903062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2012.231
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