Genome-wide analysis reveals NRP1 as a direct HIF1α-E2F7 target in the regulation of motorneuron guidance in vivo

In this study, we explored the existence of a transcriptional network co-regulated by E2F7 and HIF1α, as we show that expression of E2F7, like HIF1α, is induced in hypoxia, and because of the previously reported ability of E2F7 to interact with HIF1α. Our genome-wide analysis uncovers a transcriptio...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: de Bruin, Alain, A. Cornelissen, Peter W., Kirchmaier, Bettina C., Mokry, Michal, Iich, Elhadi, Nirmala, Ella, Liang, Kuo-Hsuan, D. Végh, Anna M., Scholman, Koen T., Groot Koerkamp, Marian J., Holstege, Frank C., Cuppen, Edwin, Schulte-Merker, Stefan, Bakker, Walbert J.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Gene regulation, Chromatin and Epigenetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4856960/
https://ncbi.nlm.nih.gov/pubmed/26681691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv1471
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