Genome-wide analysis reveals NRP1 as a direct HIF1α-E2F7 target in the regulation of motorneuron guidance in vivo

In this study, we explored the existence of a transcriptional network co-regulated by E2F7 and HIF1α, as we show that expression of E2F7, like HIF1α, is induced in hypoxia, and because of the previously reported ability of E2F7 to interact with HIF1α. Our genome-wide analysis uncovers a transcriptio...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Main Authors: de Bruin, Alain, A. Cornelissen, Peter W., Kirchmaier, Bettina C., Mokry, Michal, Iich, Elhadi, Nirmala, Ella, Liang, Kuo-Hsuan, D. Végh, Anna M., Scholman, Koen T., Groot Koerkamp, Marian J., Holstege, Frank C., Cuppen, Edwin, Schulte-Merker, Stefan, Bakker, Walbert J.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2016
Fag:
Gene regulation, Chromatin and Epigenetics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4856960/
https://ncbi.nlm.nih.gov/pubmed/26681691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv1471
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