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Delivery of interferon alpha using a novel Cox2-controlled adenovirus for pancreatic cancer therapy
BACKGROUND: Combination therapy with interferon alpha (IFN) is correlated with improved survival in patients with pancreatic ductal adenocarcinoma (PDAc) but frequently presents side effects. We designed a novel targeted adenovirus with replication restricted to cyclooxygenase 2 (Cox2)-overexpressin...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3645277/ https://ncbi.nlm.nih.gov/pubmed/22503318 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.surg.2012.02.017 |
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