Oncolytic adenovirus expressing interferon alpha in a syngeneic Syrian hamster model for the treatment of pancreatic cancer

BACKGROUND: The addition of interferon alpha (IFN) to adjuvant chemoradiotherapy regimens resulted in remarkable improvements in survival for pancreatic cancer patients. However, systemic toxicities and insufficient levels of IFN at the tumor sites have limited its widespread adoption in treatment s...

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Bibliographic Details
Published in:Surgery
Main Authors: LaRocca, Christopher J., Han, Joohee, Gavrikova, Tatyana, Armstrong, Leonard, Oliveira, Amanda R., Shanley, Ryan, Vickers, Selwyn M., Yamamoto, Masato, Davydova, Julia
Format: Artigo
Language:Inglês
Published: 2015
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4417428/
https://ncbi.nlm.nih.gov/pubmed/25731784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.surg.2015.01.006
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