Oncolytic adenovirus expressing interferon alpha in a syngeneic Syrian hamster model for the treatment of pancreatic cancer

BACKGROUND: The addition of interferon alpha (IFN) to adjuvant chemoradiotherapy regimens resulted in remarkable improvements in survival for pancreatic cancer patients. However, systemic toxicities and insufficient levels of IFN at the tumor sites have limited its widespread adoption in treatment s...

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Опубликовано в: :Surgery
Главные авторы: LaRocca, Christopher J., Han, Joohee, Gavrikova, Tatyana, Armstrong, Leonard, Oliveira, Amanda R., Shanley, Ryan, Vickers, Selwyn M., Yamamoto, Masato, Davydova, Julia
Формат: Artigo
Язык:Inglês
Опубликовано: 2015
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4417428/
https://ncbi.nlm.nih.gov/pubmed/25731784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.surg.2015.01.006
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