Oncolytic adenovirus expressing interferon alpha in a syngeneic Syrian hamster model for the treatment of pancreatic cancer

BACKGROUND: The addition of interferon alpha (IFN) to adjuvant chemoradiotherapy regimens resulted in remarkable improvements in survival for pancreatic cancer patients. However, systemic toxicities and insufficient levels of IFN at the tumor sites have limited its widespread adoption in treatment s...

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Detalhes bibliográficos
Publicado no:Surgery
Main Authors: LaRocca, Christopher J., Han, Joohee, Gavrikova, Tatyana, Armstrong, Leonard, Oliveira, Amanda R., Shanley, Ryan, Vickers, Selwyn M., Yamamoto, Masato, Davydova, Julia
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4417428/
https://ncbi.nlm.nih.gov/pubmed/25731784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.surg.2015.01.006
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