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Oncolytic adenovirus expressing interferon alpha in a syngeneic Syrian hamster model for the treatment of pancreatic cancer

BACKGROUND: The addition of interferon alpha (IFN) to adjuvant chemoradiotherapy regimens resulted in remarkable improvements in survival for pancreatic cancer patients. However, systemic toxicities and insufficient levels of IFN at the tumor sites have limited its widespread adoption in treatment s...

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Dettagli Bibliografici
Pubblicato in:Surgery
Autori principali: LaRocca, Christopher J., Han, Joohee, Gavrikova, Tatyana, Armstrong, Leonard, Oliveira, Amanda R., Shanley, Ryan, Vickers, Selwyn M., Yamamoto, Masato, Davydova, Julia
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4417428/
https://ncbi.nlm.nih.gov/pubmed/25731784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.surg.2015.01.006
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