Specific isoprenoid modification is required for function of normal, but not oncogenic, Ras protein.

While the Ras C-terminal CAAX sequence signals modification by a 15-carbon farnesyl isoprenoid, the majority of isoprenylated proteins in mammalian cells are modified instead by a 20-carbon geranylgeranyl moiety. To determine the structural and functional basis for modification of proteins by a spec...

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Dades bibliogràfiques

Publicat a:	Mol Cell Biol
Autors principals:	Cox, A D, Hisaka, M M, Buss, J E, Der, C J
Format:	Artigo
Idioma:	Inglês
Publicat:	Taylor & Francis 1992
Matèries:	Research Article
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC364454/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1375323/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.12.6.2606-2615.1992
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