Specific isoprenoid modification is required for function of normal, but not oncogenic, Ras protein.

While the Ras C-terminal CAAX sequence signals modification by a 15-carbon farnesyl isoprenoid, the majority of isoprenylated proteins in mammalian cells are modified instead by a 20-carbon geranylgeranyl moiety. To determine the structural and functional basis for modification of proteins by a spec...

Descripción completa

Detalles Bibliográficos

Publicado en:	Mol Cell Biol
Autores principales:	Cox, A D, Hisaka, M M, Buss, J E, Der, C J
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Taylor & Francis 1992
Materias:	Research Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC364454/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1375323/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.12.6.2606-2615.1992
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!