Coordinate regulation of eIF2α phosphorylation by PPP1R15 and GCN2 is required during Drosophila development

Phosphorylation of eukaryotic translation initiation factor 2 alpha (eIF2α) by the kinase GCN2 attenuates protein synthesis during amino acid starvation in yeast, whereas in mammals a family of related eIF2α kinases regulate translation in response to a variety of stresses. Unlike single-celled euka...

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Bibliografski detalji
Glavni autori: Malzer, Elke, Szajewska-Skuta, Małgorzata, Dalton, Lucy E., Thomas, Sally E., Hu, Nan, Skaer, Helen, Lomas, David A., Crowther, Damian C., Marciniak, Stefan J.
Format: Artigo
Jezik:Inglês
Izdano: The Company of Biologists 2013
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3644141/
https://ncbi.nlm.nih.gov/pubmed/23418347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.117614
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