Soluble ligands for NK cell receptors promote evasion of chronic lymphocytic leukemia cells from NK cell anti-tumor activity

Natural killer (NK) cells are a major component of the anti-tumor immune response. NK cell dysfunctions have been reported in various hematologic malignancies, including chronic lymphocytic leukemia (CLL). Here we investigated the role of tumor cell-released soluble and exosomal ligands for NK cell...

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Detalhes bibliográficos
Main Authors: Reiners, Katrin S., Topolar, Daniela, Henke, Alexander, Simhadri, Venkateswara R., Kessler, Jörg, Sauer, Maike, Bessler, Martina, Hansen, Hinrich P., Tawadros, Samir, Herling, Marco, Krönke, Martin, Hallek, Michael, Pogge von Strandmann, Elke
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2013
Assuntos:
Lymphoid Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3643764/
https://ncbi.nlm.nih.gov/pubmed/23509156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-01-476606
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