Soluble ligands for NK cell receptors promote evasion of chronic lymphocytic leukemia cells from NK cell anti-tumor activity

Natural killer (NK) cells are a major component of the anti-tumor immune response. NK cell dysfunctions have been reported in various hematologic malignancies, including chronic lymphocytic leukemia (CLL). Here we investigated the role of tumor cell-released soluble and exosomal ligands for NK cell...

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Hlavní autoři: Reiners, Katrin S., Topolar, Daniela, Henke, Alexander, Simhadri, Venkateswara R., Kessler, Jörg, Sauer, Maike, Bessler, Martina, Hansen, Hinrich P., Tawadros, Samir, Herling, Marco, Krönke, Martin, Hallek, Michael, Pogge von Strandmann, Elke
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2013
Témata:
Lymphoid Neoplasia
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3643764/
https://ncbi.nlm.nih.gov/pubmed/23509156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-01-476606
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