DNA damage response and evasion from immunosurveillance in CLL: new options for NK cell-based immunotherapies

Chronic lymphocytic leukemia (CLL) is the most prominent B cell malignancy among adults in the Western world and characterized by a clonal expansion of B cells. The patients suffer from severe immune defects resulting in increased susceptibility to infections and failure to generate an antitumor imm...

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Библиографические подробности
Опубликовано в: :Front Genet
Главные авторы: Shatnyeva, Olga M., Hansen, Hinrich P., Reiners, Katrin S., Sauer, Maike, Vyas, Maulik, von Strandmann, Elke Pogge
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2015
Предметы:
Oncology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4316781/
https://ncbi.nlm.nih.gov/pubmed/25699074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2015.00011
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