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DNA damage response and evasion from immunosurveillance in CLL: New options for NK cell-based immunotherpies.

Chronic lymphocytic leukemia (CLL) is the most prominent B cell malignancy among adults in the Western world and characterized by a clonal expansion of B cells. The patients suffer from severe immune defects resulting in increased susceptibility to infections and failure to generate an antitumor imm...

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Main Authors: Olga M. Shatnyeva, Hinrich P. Hansen, Katrin S. Reiners, Maike eSauer, Maulik eVyas, Elke ePogge Von Strandmann
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2015-02-01
Colecção:Frontiers in Genetics
Assuntos:
Acesso em linha:http://journal.frontiersin.org/Journal/10.3389/fgene.2015.00011/full
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