Two Conserved Arginine Residues from the SK3 Potassium Channel Outer Vestibule Control Selectivity of Recognition by Scorpion Toxins

Potassium channel functions are often deciphered by using selective and potent scorpion toxins. Among these toxins, only a limited subset is capable of selectively blocking small conductance Ca(2+)-activated K(+) (SK) channels. The structural bases of this selective SK channel recognition remain unc...

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Bibliografske podrobnosti
Main Authors: Feng, Jing, Hu, Youtian, Yi, Hong, Yin, Shijin, Han, Song, Hu, Jun, Chen, Zongyun, Yang, Weishan, Cao, Zhijian, De Waard, Michel, Sabatier, Jean-Marc, Li, Wenxin, Wu, Yingliang
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2013
Teme:
Protein Structure and Folding
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3642302/
https://ncbi.nlm.nih.gov/pubmed/23511633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.433888
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