Two Conserved Arginine Residues from the SK3 Potassium Channel Outer Vestibule Control Selectivity of Recognition by Scorpion Toxins

Potassium channel functions are often deciphered by using selective and potent scorpion toxins. Among these toxins, only a limited subset is capable of selectively blocking small conductance Ca(2+)-activated K(+) (SK) channels. The structural bases of this selective SK channel recognition remain unc...

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Detalhes bibliográficos
Main Authors: Feng, Jing, Hu, Youtian, Yi, Hong, Yin, Shijin, Han, Song, Hu, Jun, Chen, Zongyun, Yang, Weishan, Cao, Zhijian, De Waard, Michel, Sabatier, Jean-Marc, Li, Wenxin, Wu, Yingliang
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Protein Structure and Folding
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3642302/
https://ncbi.nlm.nih.gov/pubmed/23511633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.433888
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