Two Conserved Arginine Residues from the SK3 Potassium Channel Outer Vestibule Control Selectivity of Recognition by Scorpion Toxins

Potassium channel functions are often deciphered by using selective and potent scorpion toxins. Among these toxins, only a limited subset is capable of selectively blocking small conductance Ca(2+)-activated K(+) (SK) channels. The structural bases of this selective SK channel recognition remain unc...

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Bibliografiske detaljer
Main Authors: Feng, Jing, Hu, Youtian, Yi, Hong, Yin, Shijin, Han, Song, Hu, Jun, Chen, Zongyun, Yang, Weishan, Cao, Zhijian, De Waard, Michel, Sabatier, Jean-Marc, Li, Wenxin, Wu, Yingliang
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2013
Fag:
Protein Structure and Folding
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3642302/
https://ncbi.nlm.nih.gov/pubmed/23511633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.433888
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