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Genomic and Structural Characterization of Kunitz-Type Peptide LmKTT-1a Highlights Diversity and Evolution of Scorpion Potassium Channel Toxins

BACKGROUND: Recently, a new subfamily of long-chain toxins with a Kunitz-type fold was found in scorpion venom glands. Functionally, these toxins inhibit protease activity and block potassium channels. However, the genomic organization and three-dimensional (3-D) structure of this kind of scorpion t...

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Hlavní autoři: Chen, Zongyun, Luo, Fan, Feng, Jing, Yang, Weishan, Zeng, Danyun, Zhao, Ruiming, Cao, Zhijian, Liu, Maili, Li, Wenxin, Jiang, Ling, Wu, Yingliang
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2013
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3616063/
https://ncbi.nlm.nih.gov/pubmed/23573241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0060201
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