Anti-oncogenic activity of signalling-defective epidermal growth factor receptor mutants.

Overexpression and autocrine activation of the epidermal growth factor receptor (EGF-R) cause transformation of cultured cells and correlate with tumor progression in cancer patients. Dimerization and transphosphorylation are crucial events in the process by which receptors with tyrosine kinase acti...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Redemann, N, Holzmann, B, von Rüden, T, Wagner, E F, Schlessinger, J, Ullrich, A
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 1992
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC364201/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1346334/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.12.2.491-498.1992
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