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Functional heterogeneity of proto-oncogene tyrosine kinases: the C terminus of the human epidermal growth factor receptor facilitates cell proliferation.

Previous reports have indicated that the C termini of the membrane-associated tyrosine kinases encoded by c-src and c-fms proto-oncogenes have a negative effect on their biological activity and that this effect is mediated by their C-terminal tyrosine residue. To determine whether this was true for...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Principais autores: Velu, T J, Vass, W C, Lowy, D R, Beguinot, L
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 1989
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC362596/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2786142/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.9.4.1772-1778.1989
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