Anti-oncogenic activity of signalling-defective epidermal growth factor receptor mutants.
Overexpression and autocrine activation of the epidermal growth factor receptor (EGF-R) cause transformation of cultured cells and correlate with tumor progression in cancer patients. Dimerization and transphosphorylation are crucial events in the process by which receptors with tyrosine kinase acti...
Gardado en:
| Publicado en: | Mol Cell Biol |
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| Principais autores: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Taylor & Francis
1992
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC364201/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1346334/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.12.2.491-498.1992 |
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